BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $69,092,179
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/03/2026- NAV
- NAV Change
- Market Price $79.36
- Market Price Change $+2.67
- Trading Volume (M) 5,171
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $69,092,179
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/03/2026- NAV
- NAV Change
- Market Price $79.36
- Market Price Change $+2.67
- Trading Volume (M) 5,171
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/03/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.80% | AMGN | AMGEN INC | -- | $3,315,570.66 | 9,803 | 2023607 |
| 4.77% | GILD | GILEAD SCIENCES INC | -- | $3,294,662.58 | 25,542 | 2369174 |
| 4.75% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,279,799.38 | 7,657 | 2931034 |
| 3.44% | REGN | REGENERON PHARMACEUTICALS | -- | $2,376,768.00 | 3,840 | 2730190 |
| 2.08% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,434,812.32 | 4,904 | B00FWN1 |
| 1.65% | RVMD | REVOLUTION MEDICINES INC | -- | $1,142,782.74 | 7,326 | BL71K91 |
| 1.54% | BIIB | BIOGEN INC | -- | $1,063,083.00 | 5,425 | 2455965 |
| 1.40% | ILMN | ILLUMINA INC | -- | $966,267.29 | 5,653 | 2613990 |
| 1.29% | UTHR | UNITED THERAPEUTICS CORP | -- | $890,141.40 | 1,620 | 2430412 |
| 1.26% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $870,559.89 | 15,837 | BMVP7Y0 |
| 1.24% | ARGX | ARGENX SE - ADR | -- | $853,797.00 | 1,050 | BDVLM39 |
| 1.20% | INSM | INSMED INC | -- | $827,556.48 | 7,968 | 2614487 |
| 1.10% | ROIV | ROIVANT SCIENCES LTD | -- | $759,402.00 | 26,460 | BMW4NZ9 |
| 1.04% | INCY | INCYTE CORP | -- | $721,034.82 | 7,359 | 2471950 |
| 1.04% | MRNA | MODERNA INC | -- | $716,276.00 | 14,600 | BGSXTS3 |
| 0.96% | VTRS | VIATRIS INC | -- | $662,311.40 | 42,565 | BMWS3X9 |
| 0.89% | GH | GUARDANT HEALTH INC | -- | $616,095.50 | 4,850 | BFXC911 |
| 0.89% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $612,888.32 | 3,712 | 2623911 |
| 0.76% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $525,365.75 | 2,275 | B4Q5ZN4 |
| 0.72% | EXEL | EXELIXIS INC | -- | $495,360.00 | 9,600 | 2576941 |
| 0.71% | ASND | ASCENDIS PHARMA A/S | -- | $493,414.04 | 2,276 | BWXJHM8 |
| 0.69% | MEDP | MEDPACE HOLDINGS INC | -- | $473,806.57 | 1,051 | BDCBC61 |
| 0.68% | BBIO | BRIDGEBIO PHARMA INC | -- | $469,295.16 | 7,167 | BK1KWG8 |
| 0.65% | IONS | IONIS PHARMACEUTICALS INC | -- | $450,966.38 | 6,109 | BDJ0LS6 |
| 0.64% | AXSM | AXSOME THERAPEUTICS INC | -- | $441,296.10 | 1,890 | BYZR4X4 |
| 0.63% | SMMT | SUMMIT THERAPEUTICS INC | -- | $431,966.48 | 28,664 | BMTVQS7 |
| 0.60% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $413,463.05 | 847 | BD59BS7 |
| 0.56% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $388,632.60 | 7,110 | 2437071 |
| 0.55% | SNY | SANOFI-ADR | -- | $383,321.39 | 9,047 | 2964557 |
| 0.54% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $375,663.90 | 5,178 | BYQBFJ8 |
| 0.54% | BNTX | BIONTECH SE-ADR | -- | $372,639.85 | 4,213 | BK6H543 |
| 0.48% | ONC | BEONE MEDICINES LTD-ADR | -- | $329,499.00 | 1,181 | BYYWPW6 |
| 0.47% | KRYS | KRYSTAL BIOTECH INC | -- | $325,965.60 | 1,080 | BD6JX35 |
| 0.47% | CYTK | CYTOKINETICS INC | -- | $321,942.63 | 4,553 | BBBSBJ5 |
| 0.44% | TEM | TEMPUS AI INC-CL A | -- | $305,204.24 | 6,424 | BSLSJJ0 |
| 0.44% | HALO | HALOZYME THERAPEUTICS INC | -- | $304,694.48 | 4,364 | 2975098 |
| 0.42% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $287,018.97 | 1,029 | BQ721R4 |
| 0.39% | IBRX | IMMUNITYBIO INC | -- | $272,897.44 | 38,008 | BNSP0B8 |
| 0.38% | ALKS | ALKERMES PLC | -- | $263,529.88 | 6,163 | B3P6D26 |
| 0.36% | PCVX | VAXCYTE INC | -- | $249,714.53 | 5,321 | BKPVGH6 |
| 0.35% | NUVL | NUVALENT INC-A | -- | $243,936.90 | 2,705 | BMVBZD3 |
| 0.34% | IMVT | IMMUNOVANT INC | -- | $234,341.45 | 7,523 | BJRFSB7 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $225,263.01 | 2,361 | BDCBCD8 |
| 0.32% | KYMR | KYMERA THERAPEUTICS INC | -- | $220,874.57 | 3,017 | BMPRZV5 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $213,977.46 | 2,526 | BF2YWG4 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $213,575.60 | 2,905 | BQBBDY8 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $210,298.16 | 3,062 | B17VCN9 |
| 0.30% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $204,883.89 | 2,231 | BJDX8Y8 |
| 0.30% | ABVX | ABIVAX SA-ADR | -- | $204,730.65 | 2,271 | BLC89B2 |
| 0.28% | COGT | COGENT BIOSCIENCES INC | -- | $193,624.52 | 6,002 | BLR6XK8 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $184,884.00 | 3,550 | BDHF4K6 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $176,256.55 | 4,423 | BLB0YQ9 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $172,518.40 | 736 | 2501578 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $170,737.32 | 2,028 | BM9HHL5 |
| 0.25% | CGON | CG ONCOLOGY INC | -- | $169,953.66 | 3,123 | BRBCSP4 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $168,426.72 | 3,773 | BFZQ0L8 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $164,336.04 | 3,074 | BRJ3GY4 |
| 0.24% | TWST | TWIST BIOSCIENCE CORP | -- | $163,899.78 | 2,266 | BGKG6G7 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $163,828.32 | 4,624 | BTZRLN8 |
| 0.23% | CAI | CARIS LIFE SCIENCES INC | -- | $161,471.88 | 10,431 | BT18HP9 |
| 0.22% | TVTX | TRAVERE THERAPEUTICS INC | -- | $154,086.80 | 3,409 | BLFGJD5 |
| 0.22% | ERAS | ERASCA INC | -- | $150,831.92 | 11,444 | BNLYBF3 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $149,762.00 | 11,632 | BFNF1D6 |
| 0.21% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $143,608.86 | 3,966 | BKY5JZ8 |
| 0.21% | VCYT | VERACYTE INC | -- | $143,051.22 | 2,938 | BFTWZY0 |
| 0.20% | TXG | 10X GENOMICS INC-CLASS A | -- | $139,928.16 | 4,351 | BKS3RS7 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $136,531.72 | 4,252 | BP8JSP4 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $135,073.29 | 6,303 | 2713317 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $128,124.48 | 3,872 | BDD19F8 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $115,266.58 | 5,863 | BD2B4V0 |
| 0.16% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $112,329.56 | 3,122 | BMX9K07 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $111,314.85 | 3,767 | BK6L288 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $109,505.13 | 6,087 | BN15WD1 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $108,000.00 | 2,880 | BQS9486 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $106,877.66 | 4,978 | BP2P6L0 |
| 0.15% | ORKA | ORUKA THERAPEUTICS INC | -- | $102,330.80 | 1,789 | BKVF0J2 |
| 0.15% | RLAY | RELAY THERAPEUTICS INC | -- | $101,071.80 | 6,606 | BN2R582 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $99,263.85 | 1,411 | BMGJZJ8 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $97,932.45 | 4,587 | BKX9VD3 |
| 0.14% | ALMS | ALUMIS INC | -- | $93,853.92 | 4,674 | BPLQG36 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $93,354.20 | 2,120 | B72ZBG4 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $92,429.48 | 1,573 | BMH5RL1 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $92,186.40 | 3,246 | BK0VHF6 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $91,015.08 | 5,692 | BJ5FZ74 |
| 0.13% | GRAL | GRAIL INC | -- | $87,966.07 | 1,439 | BSLSSX7 |
| 0.13% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $86,929.15 | 3,685 | BV2DHY6 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $82,427.72 | 2,636 | BL55460 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $81,249.30 | 1,698 | BRXB0C0 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $80,026.11 | 3,571 | BJ62Z18 |
| 0.11% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $79,121.88 | 2,196 | BMFD115 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $77,002.38 | 4,914 | BFWLC09 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $76,485.75 | 9,271 | 2100362 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $76,376.85 | 2,255 | BFXC933 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $73,300.50 | 2,925 | BP9N0G0 |
| 0.10% | PHVS | PHARVARIS NV | -- | $71,341.38 | 2,367 | BMZ2X38 |
| 0.10% | QURE | UNIQURE NV | -- | $68,873.40 | 2,305 | BJFSR88 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $68,694.00 | 2,140 | BKSGZN7 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $68,326.80 | 8,805 | B9NSBM2 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $67,975.35 | 4,209 | BYSS4X4 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $67,352.10 | 2,766 | BPCQZY9 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $67,209.15 | 8,049 | BNZB1X8 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $66,960.59 | 19,297 | BM9FJ13 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $65,268.00 | 1,764 | BR3T9B6 |
| 0.09% | VCEL | VERICEL CORP | -- | $65,137.50 | 1,875 | BSBMN89 |
| 0.09% | ABCL | ABCELLERA BIOLOGICS INC | -- | $64,115.48 | 11,209 | BL53SR3 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $63,779.90 | 4,742 | BJH9ZN0 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $62,930.00 | 3,875 | B8DPDT7 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $62,440.90 | 830 | BCDWBX6 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $62,190.06 | 2,111 | BJQ05Z6 |
| 0.09% | NVAX | NOVAVAX INC | -- | $61,434.60 | 6,023 | BJDQXG4 |
| 0.09% | ATAI | ATAIBECKLEY INC | -- | $60,833.37 | 13,429 | BWJDYK1 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $60,591.70 | 1,651 | BQKXDX4 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $59,954.88 | 2,166 | BCBVTX1 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $59,806.74 | 3,261 | BN7Q7R7 |
| 0.09% | INVA | INNOVIVA INC | -- | $59,458.00 | 2,740 | BDDXF67 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $58,854.96 | 3,802 | BMVLGP2 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $57,729.28 | 15,232 | BF0DMK7 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $56,884.38 | 4,369 | BYZM6C2 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $56,810.52 | 2,379 | BBC9WC7 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $56,634.06 | 1,974 | BMVNDH9 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $56,210.40 | 10,128 | BNC1BX1 |
| 0.08% | GHRS | GH RESEARCH PLC | -- | $56,042.42 | 2,294 | BP6C0S2 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $54,001.65 | 3,455 | BRXYZ57 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $53,578.80 | 4,059 | BPCK358 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $52,418.52 | 1,023 | BDRW1L7 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $51,133.14 | 537 | BNSP8K3 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $50,953.70 | 5,810 | BK4PZ38 |
| 0.07% | SEPN | SEPTERNA INC | -- | $50,621.35 | 1,657 | BQNKXX2 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,396.50 | 1,870 | BD06CS0 |
| 0.07% | PGEN | PRECIGEN INC | -- | $49,834.80 | 13,080 | BKM5C84 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $49,822.90 | 1,658 | BQXJKH2 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $49,568.62 | 2,818 | BP7KZP7 |
| 0.07% | ARDX | ARDELYX INC | -- | $49,137.72 | 9,066 | BN89V40 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $46,860.00 | 2,343 | BQB42F1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,441.65 | 1,621 | BLCD809 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $46,018.00 | 1,730 | BZ7PJQ1 |
| 0.07% | HROW | HARROW INC | -- | $45,648.40 | 1,370 | BHNDW86 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $45,474.06 | 1,527 | BMGTLY5 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $44,250.03 | 3,487 | BMC3HS7 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $44,201.08 | 1,778 | BSRK699 |
| 0.06% | PSNL | PERSONALIS INC | -- | $41,707.82 | 3,869 | BJQ0608 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $40,089.60 | 6,960 | BYZG9R0 |
| 0.06% | SVRA | SAVARA INC | -- | $39,501.00 | 7,524 | BYXGN81 |
| 0.06% | ALVO | ALVOTECH SA | -- | $38,339.40 | 12,210 | BPNTJ34 |
| 0.06% | MNKD | MANNKIND CORP | -- | $38,267.04 | 11,389 | BF081J4 |
| 0.05% | EYPT | EYEPOINT INC | -- | $37,785.08 | 3,062 | BMGS7L1 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $36,402.32 | 1,172 | BX7RSN3 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $36,129.26 | 6,134 | BLR7H87 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $35,426.40 | 3,054 | BYP80F1 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $34,504.20 | 1,983 | BQB42H3 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $33,689.70 | 4,510 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $33,368.40 | 1,495 | B3X26D8 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $33,233.85 | 2,185 | BM90J52 |
| 0.05% | ABSI | ABSCI CORP | -- | $33,032.34 | 5,561 | BN94K69 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $31,990.00 | 3,656 | BMCR7V2 |
| 0.05% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $31,130.62 | 2,962 | BMZ4LN0 |
| 0.04% | XNCR | XENCOR INC | -- | $30,959.62 | 2,711 | BGCYWN8 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,928.50 | 7,110 | BZ0QMB7 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $30,728.88 | 9,849 | BMFJJ97 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,591.09 | 2,251 | BMFX8Y7 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $30,468.94 | 3,053 | BDDVW37 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $30,387.24 | 1,677 | BNFWZS4 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $29,850.00 | 1,875 | BMNDK09 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $29,382.08 | 2,912 | BJLKVS6 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $29,094.24 | 3,711 | BKVDFF7 |
| 0.04% | ANNX | ANNEXON INC | -- | $28,831.11 | 5,349 | BMVV9R5 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $28,081.68 | 1,934 | BQS7491 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,935.25 | 2,975 | BFYQFJ2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $27,851.79 | 3,218 | BYZD465 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,748.18 | 8,837 | BBNBTD2 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $27,389.12 | 992 | BGL0JK3 |
| 0.04% | GERN | GERON CORP | -- | $27,378.32 | 23,602 | 2370381 |
| 0.04% | OMER | OMEROS CORP | -- | $26,639.52 | 2,622 | B4NB858 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $26,184.40 | 5,410 | BMCWKZ2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $25,728.16 | 1,604 | BT9K6D8 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $24,255.77 | 763 | BL95N25 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,957.53 | 2,911 | BJ0LT31 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $23,821.60 | 2,707 | BP0TQC5 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,829.68 | 2,083 | BLFBZ32 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,429.00 | 1,100 | BKLCWZ3 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $21,976.20 | 2,105 | BMFK3H6 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $21,788.73 | 1,269 | BD9GVY0 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $20,953.22 | 6,673 | BPBJFM7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $20,643.84 | 1,536 | BRJJYT3 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,361.60 | 672 | BQD3J33 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $20,173.30 | 6,265 | BYWVTY5 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $19,728.00 | 2,880 | BQHN6C7 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,708.78 | 4,459 | BYV2W40 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $19,695.06 | 693 | BPBPCG8 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $19,530.72 | 6,028 | B3MZ6K5 |
| 0.03% | ARVN | ARVINAS INC | -- | $18,195.10 | 2,363 | BDZ30Q0 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,179.33 | 4,511 | BYVQJ96 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $17,964.05 | 1,885 | BKLXFX5 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $17,741.88 | 1,989 | B91XRN2 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,637.54 | 11,163 | B4N8MH9 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $16,616.00 | 8,308 | BFZNYB7 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,515.84 | 2,112 | BSMLR16 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,161.12 | 2,349 | BP81R42 |
| 0.02% | KMDA | KAMADA LTD | -- | $15,770.26 | 2,134 | B2Q9833 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $15,672.36 | 1,023 | BS2CR64 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $15,237.11 | 1,997 | BRCFFK6 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,075.48 | 548 | B292NQ7 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,971.62 | 571 | BS2F741 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,453.91 | 2,397 | BDRJH21 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $14,291.64 | 3,609 | BKX9NQ0 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $14,027.52 | 1,124 | BPRBTY7 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,312.74 | 2,186 | B12W3P6 |
| 0.02% | OABI | OMNIAB INC | -- | $13,305.00 | 5,322 | BN13S71 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,290.97 | 4,631 | BFY7DC4 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $12,844.80 | 4,014 | BMXNGZ6 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $12,795.99 | 1,879 | B7F2TY6 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,734.06 | 3,557 | BK5MWR1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $12,530.37 | 1,873 | BZ0G875 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,162.69 | 2,889 | BLN9Z50 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $12,136.50 | 2,697 | BQ6C357 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,049.28 | 1,072 | B9L5200 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,010.68 | 7,414 | BFMLGR4 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,812.50 | 1,125 | BM7V485 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,717.96 | 4,013 | BDFKQ07 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,351.34 | 2,646 | 2107437 |
| 0.02% | IVVD | INVIVYD INC | -- | $11,268.40 | 10,244 | BM8NHS1 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,127.76 | 1,736 | BL5B6Z1 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,860.85 | 2,387 | BMVBZF5 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,746.24 | 6,176 | BN4JN37 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $10,162.53 | 1,981 | BP7L561 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $10,038.58 | 3,611 | BZ8FPH3 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,990.40 | 7,136 | BMYTJP4 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $9,892.59 | 787 | BTNMG41 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,317.28 | 1,416 | BP81RK8 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,087.52 | 3,341 | B5LL2C2 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $9,061.77 | 3,426 | BYTYP72 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,893.19 | 3,721 | BZC0D70 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,603.70 | 7,230 | BNR5QT9 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,121.75 | 5,525 | BRK0149 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $8,117.58 | 1,158 | BQV0J03 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,063.54 | 2,089 | BPRB2N7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,995.20 | 1,052 | BKC9SX3 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $7,934.08 | 2,464 | BJDX8Z9 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $7,880.60 | 2,165 | BMF7DT9 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,868.42 | 1,147 | BP2NYN2 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,864.29 | 1,387 | 2517058 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,844.40 | 2,179 | BY7RB53 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,264.25 | 4,151 | BKRRKY7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,186.20 | 1,711 | BKDQKM6 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,908.00 | 3,454 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,295.83 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,732.87 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,420.50 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,915.10 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,608.22 | 2,541 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,157.36 | 3,608 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,063.24 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,610.91 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 29.62% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,464,643 | -- | 3,524 | -- |
| 28.36% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,593,560 | -- | 3,374 | -- |
| 28.29% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 19,547,103 | -- | 3,366 | -- |
| 22.18% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,325,254 | -- | 2,639 | -- |
| 21.12% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,593,544 | -- | 2,513 | -- |
| 5.32% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,675,970 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,003,500.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $19,073,862.32 | 19,073,862 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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