BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 1/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 9.81% | -6.82% | -15.88% | 9.81% | -1.10% | -3.16% | 0.64% | -2.11% | 14.62% | 04/07/2010 |
| BIB NAV | 9.75% | -7.11% | -15.96% | 9.75% | -1.12% | -3.31% | 0.62% | -2.13% | 14.61% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -14.25% | -19.94% | -13.65% | -9.84% | -9.84% | -14.06% | -3.57% | -1.96% | 13.98% | 04/07/2010 |
| BIB NAV | -14.45% | -20.03% | -13.70% | -10.00% | -10.00% | -14.09% | -3.57% | -1.97% | 13.97% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/03/2025- NAV $52.73
- NAV Change $-2.23
- Market Price $52.86
- Market Price Change $-2.14
- Trading Volume (M) 7,865
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/03/2025- NAV $52.73
- NAV Change $-2.23
- Market Price $52.86
- Market Price Change $-2.14
- Trading Volume (M) 7,865
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2024
Holdings
as of 3/03/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 7.94% | GILD | GILEAD SCIENCES INC | -- | $4,688,547.78 | 40,422 | 2369174 |
| 6.96% | AMGN | AMGEN INC | -- | $4,112,551.74 | 13,233 | 2023607 |
| 6.54% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,863,580.14 | 7,994 | 2931034 |
| 5.42% | REGN | REGENERON PHARMACEUTICALS | -- | $3,201,082.38 | 4,674 | 2730190 |
| 3.25% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,917,035.10 | 25,191 | 2989044 |
| 2.30% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,359,384.46 | 5,582 | B00FWN1 |
| 1.51% | BIIB | BIOGEN INC | -- | $892,773.00 | 6,300 | 2455965 |
| 1.47% | ARGX | ARGENX SE - ADR | -- | $867,918.34 | 1,394 | BDVLM39 |
| 1.25% | SNY | SANOFI-ADR | -- | $736,003.44 | 13,022 | 2964557 |
| 1.10% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $650,619.90 | 19,215 | BMVP7Y0 |
| 1.03% | SMMT | SUMMIT THERAPEUTICS INC | -- | $610,151.35 | 31,895 | BMTVQS7 |
| 1.02% | ITCI | INTRA-CELLULAR THERAPIES INC | -- | $601,787.52 | 4,584 | BHCB0P4 |
| 1.01% | UTHR | UNITED THERAPEUTICS CORP | -- | $598,667.93 | 1,931 | 2430412 |
| 1.00% | INSM | INSMED INC | -- | $590,332.02 | 7,738 | 2614487 |
| 0.99% | INCY | INCYTE CORP | -- | $585,476.58 | 8,333 | 2471950 |
| 0.99% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $585,417.86 | 8,243 | 2437071 |
| 0.98% | ILMN | ILLUMINA INC | -- | $577,527.80 | 6,859 | 2613990 |
| 0.85% | MRNA | MODERNA INC | -- | $503,934.96 | 16,648 | BGSXTS3 |
| 0.85% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $501,422.40 | 4,380 | 2623911 |
| 0.82% | VTRS | VIATRIS INC | -- | $481,651.92 | 51,624 | BMWS3X9 |
| 0.81% | EXEL | EXELIXIS INC | -- | $476,246.70 | 12,354 | 2576941 |
| 0.80% | BNTX | BIONTECH SE-ADR | -- | $473,906.88 | 4,248 | BK6H543 |
| 0.80% | ONC | BEIGENE LTD-ADR | -- | $470,435.48 | 1,916 | BYYWPW6 |
| 0.73% | MEDP | MEDPACE HOLDINGS INC | -- | $430,241.16 | 1,348 | BDCBC61 |
| 0.71% | SRPT | SAREPTA THERAPEUTICS INC | -- | $417,937.38 | 4,129 | B8DPDT7 |
| 0.67% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $396,385.37 | 2,609 | BV9G6B8 |
| 0.66% | PCVX | VAXCYTE INC | -- | $388,763.20 | 5,392 | BKPVGH6 |
| 0.62% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $366,815.52 | 2,616 | B4Q5ZN4 |
| 0.57% | TEM | TEMPUS AI INC | -- | $335,730.56 | 6,592 | BSLSJJ0 |
| 0.54% | ROIV | ROIVANT SCIENCES LTD | -- | $320,202.45 | 31,485 | BMW4NZ9 |
| 0.54% | HALO | HALOZYME THERAPEUTICS INC | -- | $319,243.68 | 5,508 | 2975098 |
| 0.50% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $295,288.74 | 942 | BD59BS7 |
| 0.47% | RVMD | REVOLUTION MEDICINES INC | -- | $278,885.16 | 7,274 | BL71K91 |
| 0.46% | BBIO | BRIDGEBIO PHARMA INC | -- | $269,889.76 | 8,176 | BK1KWG8 |
| 0.45% | AXSM | AXSOME THERAPEUTICS INC | -- | $266,379.25 | 2,095 | BYZR4X4 |
| 0.42% | BPMC | BLUEPRINT MEDICINES CORP | -- | $246,274.00 | 2,744 | BWY52P3 |
| 0.40% | ALKS | ALKERMES PLC | -- | $238,667.67 | 6,997 | B3P6D26 |
| 0.38% | IONS | IONIS PHARMACEUTICALS INC | -- | $222,592.80 | 6,828 | BDJ0LS6 |
| 0.37% | CYTK | CYTOKINETICS INC | -- | $218,781.89 | 5,101 | BBBSBJ5 |
| 0.37% | GH | GUARDANT HEALTH INC | -- | $217,673.82 | 5,343 | BFXC911 |
| 0.36% | KRYS | KRYSTAL BIOTECH INC | -- | $214,100.18 | 1,246 | BD6JX35 |
| 0.36% | VRNA | VERONA PHARMA PLC - ADR | -- | $211,104.00 | 3,200 | BYWPZK5 |
| 0.34% | NUVL | NUVALENT INC-A | -- | $201,370.05 | 2,835 | BMVBZD3 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $176,374.32 | 3,336 | B17VCN9 |
| 0.29% | SWTX | SPRINGWORKS THERAPEUTICS INC | -- | $171,561.60 | 3,220 | BGMGM89 |
| 0.28% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $164,833.70 | 3,995 | BJ62Z18 |
| 0.27% | ADMA | ADMA BIOLOGICS INC | -- | $161,845.92 | 10,224 | B9NSBM2 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $156,092.39 | 3,691 | BDHF4K6 |
| 0.26% | RNA | AVIDITY BIOSCIENCES INC | -- | $150,892.08 | 5,164 | BMWHPY1 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $146,948.88 | 4,056 | BFZQ0L8 |
| 0.25% | ACLX | ARCELLX INC | -- | $146,366.31 | 2,337 | BPCJ1Q2 |
| 0.24% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $139,069.60 | 2,654 | BF2YWG4 |
| 0.23% | AKRO | AKERO THERAPEUTICS INC | -- | $137,439.72 | 3,018 | BK7Y2V9 |
| 0.23% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $136,969.68 | 4,012 | BDD19F8 |
| 0.23% | MRUS | MERUS NV | -- | $134,773.08 | 2,964 | BZBY005 |
| 0.22% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $130,643.04 | 7,194 | 2713317 |
| 0.22% | APLS | APELLIS PHARMACEUTICALS INC | -- | $129,442.80 | 5,380 | BYTQ6X1 |
| 0.22% | ALVO | ALVOTECH SA | -- | $128,127.30 | 11,543 | BPNTJ34 |
| 0.20% | XENE | XENON PHARMACEUTICALS INC | -- | $118,107.00 | 3,300 | BRJ3GY4 |
| 0.20% | FOLD | AMICUS THERAPEUTICS INC | -- | $117,996.12 | 12,924 | B19FQ48 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $117,427.80 | 13,405 | BFNF1D6 |
| 0.20% | IMVT | IMMUNOVANT INC | -- | $117,094.00 | 6,350 | BJRFSB7 |
| 0.20% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $116,518.34 | 3,533 | BMX9K07 |
| 0.19% | VCYT | VERACYTE INC | -- | $112,426.00 | 3,350 | BFTWZY0 |
| 0.18% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $108,833.85 | 16,515 | BM9FJ13 |
| 0.18% | VCEL | VERICEL CORP | -- | $105,703.85 | 2,135 | BSBMN89 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $104,570.88 | 4,096 | BKY5JZ8 |
| 0.17% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $99,099.00 | 2,574 | BDCBCD8 |
| 0.16% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $95,521.23 | 2,077 | BJDX8Y8 |
| 0.16% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $95,315.22 | 5,382 | BYQBFJ8 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $95,224.26 | 2,566 | BGKG6G7 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $94,620.00 | 6,225 | BD2B4V0 |
| 0.16% | LGND | LIGAND PHARMACEUTICALS | -- | $91,763.24 | 818 | 2501578 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $89,883.10 | 3,581 | BK6L288 |
| 0.15% | NVCR | NOVOCURE LTD | -- | $86,158.80 | 4,680 | BYSS4X4 |
| 0.15% | IBRX | IMMUNITYBIO INC | -- | $85,907.55 | 30,143 | BNSP0B8 |
| 0.14% | KYMR | KYMERA THERAPEUTICS INC | -- | $84,626.85 | 2,805 | BMPRZV5 |
| 0.14% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $81,806.40 | 2,470 | BCBVTX1 |
| 0.14% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $80,978.65 | 3,995 | BP8JSP4 |
| 0.13% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $79,484.60 | 2,470 | BKSGZN7 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $77,672.94 | 2,734 | BL55460 |
| 0.13% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $76,863.93 | 5,681 | BRJZSK0 |
| 0.13% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $76,501.32 | 8,958 | 2100362 |
| 0.13% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $75,826.86 | 2,389 | B72ZBG4 |
| 0.12% | TVTX | TRAVERE THERAPEUTICS INC | -- | $73,477.80 | 3,711 | BLFGJD5 |
| 0.12% | CGON | CG ONCOLOGY INC | -- | $73,367.30 | 2,923 | BRBCSP4 |
| 0.12% | JANX | JANUX THERAPEUTICS INC | -- | $72,254.10 | 2,270 | BMFX8Y7 |
| 0.12% | IDYA | IDEAYA BIOSCIENCES INC | -- | $71,527.07 | 3,739 | BK0VHF6 |
| 0.12% | ZLAB | ZAI LAB LTD-ADR | -- | $71,519.42 | 2,254 | BD9GVY0 |
| 0.12% | TARS | TARSUS PHARMACEUTICALS INC | -- | $70,658.88 | 1,654 | BMH5RL1 |
| 0.12% | IRON | DISC MEDICINE INC | -- | $69,868.38 | 1,286 | BMGJZJ8 |
| 0.11% | WVE | WAVE LIFE SCIENCES LTD | -- | $66,309.90 | 6,598 | BYZG9R0 |
| 0.11% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $64,983.95 | 5,065 | BKX9VD3 |
| 0.10% | APGE | APOGEE THERAPEUTICS INC | -- | $61,179.11 | 1,949 | BM9HHL5 |
| 0.10% | MNKD | MANNKIND CORP | -- | $61,052.13 | 11,901 | BF081J4 |
| 0.10% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $58,054.40 | 3,860 | BLB0YQ9 |
| 0.10% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $57,480.82 | 2,573 | BQS9486 |
| 0.10% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $57,269.12 | 2,081 | BNFWZS4 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $57,136.68 | 3,691 | BN7Q7R7 |
| 0.10% | INDV | INDIVIOR PLC | -- | $56,325.90 | 5,898 | BP0BQQ5 |
| 0.09% | NVAX | NOVAVAX INC | -- | $54,602.06 | 6,938 | BJDQXG4 |
| 0.09% | DYN | DYNE THERAPEUTICS INC | -- | $54,220.32 | 4,401 | BN15WD1 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $53,257.06 | 911 | BCDWBX6 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $53,247.20 | 13,180 | BF0DMK7 |
| 0.09% | GRAL | GRAIL INC | -- | $52,751.16 | 1,452 | BSLSSX7 |
| 0.09% | ARDX | ARDELYX INC | -- | $52,029.36 | 10,242 | BN89V40 |
| 0.09% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $51,694.20 | 6,382 | BJ5FZ74 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $49,442.56 | 1,712 | BLCD809 |
| 0.08% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $49,420.14 | 6,193 | BFWLC09 |
| 0.08% | ARVN | ARVINAS INC | -- | $48,300.48 | 2,976 | BDZ30Q0 |
| 0.08% | INVA | INNOVIVA INC | -- | $48,210.90 | 2,710 | BDDXF67 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $47,163.60 | 5,955 | BK4PZ38 |
| 0.08% | PCRX | PACIRA BIOSCIENCES INC | -- | $45,874.08 | 1,998 | B3X26D8 |
| 0.08% | TXG | 10X GENOMICS INC-CLASS A | -- | $45,585.80 | 4,628 | BKS3RS7 |
| 0.08% | SYRE | SPYRE THERAPEUTICS INC | -- | $45,567.60 | 2,540 | BQBBDY8 |
| 0.08% | GRFS | GRIFOLS SA-ADR | -- | $45,250.92 | 5,274 | B8K7T65 |
| 0.08% | ETNB | 89BIO INC | -- | $45,172.56 | 5,087 | BK1K484 |
| 0.08% | GERN | GERON CORP | -- | $44,714.79 | 26,149 | 2370381 |
| 0.07% | XNCR | XENCOR INC | -- | $43,770.42 | 3,027 | BGCYWN8 |
| 0.07% | NRIX | NURIX THERAPEUTICS INC | -- | $43,492.35 | 3,065 | BMVLGP2 |
| 0.07% | SPRY | ARS PHARMACEUTICALS INC | -- | $42,786.54 | 4,203 | BMCR7V2 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $41,627.25 | 4,405 | BYZM6C2 |
| 0.07% | GMAB | GENMAB A/S -SP ADR | -- | $41,626.48 | 1,813 | BBC9WC7 |
| 0.07% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $41,496.30 | 2,115 | BMFD115 |
| 0.07% | REPL | REPLIMUNE GROUP INC | -- | $40,335.36 | 3,328 | BDDVW37 |
| 0.07% | OCUL | OCULAR THERAPEUTIX INC | -- | $40,301.85 | 6,802 | BNZB1X8 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $40,243.26 | 3,877 | BRXYZ57 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $39,645.36 | 1,394 | BX7RSN3 |
| 0.07% | HROW | HARROW INC | -- | $39,470.20 | 1,540 | BHNDW86 |
| 0.07% | EOLS | EVOLUS INC | -- | $39,205.56 | 2,734 | BDRJH21 |
| 0.07% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $38,585.08 | 1,798 | BRXB0C0 |
| 0.06% | ZYME | ZYMEWORKS INC | -- | $37,965.20 | 2,980 | BPCQZY9 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $36,003.00 | 4,364 | BLB0YH0 |
| 0.06% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $34,676.55 | 3,945 | BDFKQ07 |
| 0.06% | COGT | COGENT BIOSCIENCES INC | -- | $33,432.00 | 4,776 | BLR6XK8 |
| 0.06% | PRTA | PROTHENA CORP PLC | -- | $33,302.92 | 2,324 | B91XRN2 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $32,097.71 | 1,457 | BMGTLY5 |
| 0.05% | AVDL | AVADEL PHARMACEUTICALS | -- | $31,460.85 | 4,167 | BDGMC59 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $30,326.09 | 3,667 | BYTYP72 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $30,146.64 | 12,774 | BL53SR3 |
| 0.05% | CVAC | CUREVAC NV | -- | $29,885.24 | 9,703 | BN4RD42 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $28,047.42 | 8,201 | BZ0QMB7 |
| 0.05% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $27,041.30 | 806 | BQ721R4 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $25,779.24 | 1,212 | BKLCWZ3 |
| 0.04% | LENZ | LENZ THERAPEUTICS INC | -- | $25,567.98 | 1,187 | BQV0J03 |
| 0.04% | CRMD | CORMEDIX INC | -- | $25,192.93 | 2,627 | BJ0LT31 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $24,538.69 | 2,189 | BMVNDH9 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $24,381.75 | 3,363 | BYZD465 |
| 0.04% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $23,793.12 | 6,448 | BLR7H87 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $23,471.37 | 9,659 | BMFJJ97 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $23,340.20 | 3,055 | BKVDFF7 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $23,171.20 | 7,241 | BN2R582 |
| 0.04% | QURE | UNIQURE NV | -- | $22,988.10 | 2,109 | BJFSR88 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $22,913.96 | 2,108 | BD06CS0 |
| 0.04% | VERV | VERVE THERAPEUTICS INC | -- | $22,588.37 | 3,661 | BNKGXX2 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $21,915.36 | 3,382 | BFYQFJ2 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $21,602.12 | 881 | BL95N25 |
| 0.04% | HCM | HUTCHMED CHINA-ADR | -- | $21,398.95 | 1,345 | BYXV9H7 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $21,312.03 | 1,383 | BQS7491 |
| 0.04% | PGEN | PRECIGEN INC | -- | $21,153.89 | 12,667 | BKM5C84 |
| 0.03% | OMER | OMEROS CORP | -- | $20,457.68 | 2,504 | B4NB858 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $20,144.00 | 2,518 | BM90J52 |
| 0.03% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $19,924.41 | 1,903 | BKDQKM6 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $19,469.40 | 1,754 | BM7V485 |
| 0.03% | TBPH | THERAVANCE BIOPHARMA INC | -- | $19,452.90 | 2,126 | BMNDK09 |
| 0.03% | MLYS | MINERALYS THERAPEUTICS INC | -- | $19,310.40 | 2,160 | BP9N0G0 |
| 0.03% | ANAB | ANAPTYSBIO INC | -- | $19,266.24 | 1,316 | BDRW1L7 |
| 0.03% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $19,250.00 | 1,100 | BQB9HM8 |
| 0.03% | MNMD | MIND MEDICINE MINDMED INC | -- | $19,235.83 | 3,169 | BPQYY97 |
| 0.03% | SAGE | SAGE THERAPEUTICS INC | -- | $19,087.20 | 2,651 | BP4GNK9 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $18,524.68 | 6,134 | BMCWKZ2 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $18,425.24 | 3,076 | BFY7DC4 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $18,361.28 | 1,171 | BKC9SX3 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $18,309.28 | 1,616 | BP81RK8 |
| 0.03% | OABI | OMNIAB INC | -- | $17,910.54 | 5,237 | BN13S71 |
| 0.03% | SVRA | SAVARA INC | -- | $17,219.04 | 7,422 | BYXGN81 |
| 0.03% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $17,091.36 | 2,988 | BMGS7L1 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $17,068.31 | 763 | BQD3J33 |
| 0.03% | HUMA | HUMACYTE INC | -- | $17,007.19 | 5,567 | BMYTJP4 |
| 0.03% | ABSI | ABSCI CORP | -- | $16,990.56 | 4,968 | BN94K69 |
| 0.03% | STOK | STOKE THERAPEUTICS INC | -- | $16,975.60 | 2,294 | BJQ05Z6 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $16,932.30 | 2,310 | BLFBZ32 |
| 0.03% | URGN | UROGEN PHARMA LTD | -- | $16,927.02 | 1,826 | BZ7PJQ1 |
| 0.03% | SIGA | SIGA TECHNOLOGIES INC | -- | $16,628.15 | 3,085 | 2107437 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $16,320.60 | 9,067 | BFZNYB7 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $15,749.94 | 606 | B292NQ7 |
| 0.03% | ERAS | ERASCA INC | -- | $15,653.12 | 12,229 | BNLYBF3 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $15,580.81 | 2,161 | BP81R42 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $15,573.55 | 11,843 | B4N8MH9 |
| 0.03% | MXCT | MAXCYTE INC | -- | $15,553.01 | 4,561 | BKMQF66 |
| 0.03% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $15,416.39 | 2,959 | BJLKVS6 |
| 0.03% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $15,109.50 | 8,634 | BFMLGR4 |
| 0.03% | ORKA | ORUKA THERAPEUTICS INC | -- | $15,003.74 | 1,514 | BKVF0J2 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $14,935.58 | 638 | BPBPCG8 |
| 0.03% | ATXS | ASTRIA THERAPEUTICS INC | -- | $14,890.10 | 2,441 | BMYRFN8 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $14,724.15 | 2,653 | BP7KZP7 |
| 0.02% | TSHA | TAYSHA GENE THERAPIES INC | -- | $14,361.30 | 8,865 | BNC1BX1 |
| 0.02% | TRVI | TREVI THERAPEUTICS INC | -- | $14,155.98 | 3,323 | BJH9ZN0 |
| 0.02% | TRML | TOURMALINE BIO INC | -- | $13,649.31 | 1,107 | BQ80NC6 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $13,513.16 | 2,306 | BP7L561 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $13,471.08 | 8,526 | BBNBTD2 |
| 0.02% | RGNX | REGENXBIO INC | -- | $12,692.48 | 2,144 | BZ0G875 |
| 0.02% | PRME | PRIME MEDICINE INC | -- | $12,681.39 | 5,674 | BPBJFM7 |
| 0.02% | PSNL | PERSONALIS INC | -- | $12,572.49 | 3,059 | BJQ0608 |
| 0.02% | TERN | TERNS PHARMACEUTICALS INC | -- | $12,454.86 | 3,674 | BMDJ0C9 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $11,903.84 | 2,522 | B12W3P6 |
| 0.02% | SLRN | ACELYRIN INC | -- | $11,671.91 | 4,339 | BQPF874 |
| 0.02% | RAPP | RAPPORT THERAPEUTICS INC | -- | $11,325.60 | 1,584 | BR3T9B6 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $11,074.00 | 2,450 | BMFK3H6 |
| 0.02% | ITOS | ITEOS THERAPEUTICS INC | -- | $11,058.18 | 1,582 | BMWXFT4 |
| 0.02% | ANNX | ANNEXON INC | -- | $11,022.68 | 4,612 | BMVV9R5 |
| 0.02% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $10,981.00 | 2,780 | BYP80F1 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $10,596.60 | 3,654 | BLN9Z50 |
| 0.02% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $10,519.92 | 6,921 | B3MZ6K5 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $10,456.90 | 3,946 | BYVQJ96 |
| 0.02% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $10,436.59 | 2,479 | BMZ4LN0 |
| 0.02% | NGNE | NEUROGENE INC | -- | $10,423.03 | 643 | BS2F741 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $10,385.28 | 2,404 | BMF7DT9 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $10,272.00 | 4,280 | BZC0D70 |
| 0.02% | YMAB | Y-MABS THERAPEUTICS INC | -- | $10,058.22 | 1,938 | BG31GH0 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,813.93 | 6,985 | BN4JN37 |
| 0.02% | CDXS | CODEXIS INC | -- | $9,621.73 | 3,518 | B5LL2C2 |
| 0.02% | ALMS | ALUMIS INC | -- | $9,270.68 | 2,042 | BPLQG36 |
| 0.02% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,243.24 | 2,364 | BY7RB53 |
| 0.02% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $8,934.96 | 7,572 | BPG5P75 |
| 0.02% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $8,904.00 | 2,968 | BPCK358 |
| 0.01% | SLDB | SOLID BIOSCIENCES INC | -- | $8,842.24 | 1,727 | BQHN6C7 |
| 0.01% | AMRN | AMARIN CORP PLC -ADR | -- | $8,828.10 | 17,310 | 2301938 |
| 0.01% | TNGX | TANGO THERAPEUTICS INC | -- | $8,825.50 | 4,645 | BP2P6L0 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $8,786.88 | 2,034 | BL5B6Z1 |
| 0.01% | INBX | INHIBRX BIOSCIENCES INC | -- | $8,514.66 | 627 | BNSP8K3 |
| 0.01% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $8,275.86 | 1,999 | BKLXFX5 |
| 0.01% | CMPS | COMPASS PATHWAYS PLC | -- | $8,077.67 | 2,201 | BMC3HS7 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $7,987.07 | 12,076 | BN6MB18 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $7,334.40 | 3,056 | BKX9NQ0 |
| 0.01% | CRGX | CARGO THERAPEUTICS INC | -- | $7,326.88 | 1,991 | BQHN2F2 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $7,308.70 | 2,758 | BMXNGZ6 |
| 0.01% | SCPH | SCPHARMACEUTICALS INC | -- | $6,936.81 | 2,161 | BYX2Z16 |
| 0.01% | ACRV | ACRIVON THERAPEUTICS INC | -- | $6,903.02 | 1,343 | BP2TPK4 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $6,714.28 | 916 | B9L5200 |
| 0.01% | THRD | THIRD HARMONIC BIO INC | -- | $6,711.44 | 1,951 | BNNPQY8 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $6,320.67 | 3,571 | BZ8FPH3 |
| 0.01% | MGNX | MACROGENICS INC | -- | $6,197.04 | 2,718 | BFDV8K0 |
| 0.01% | ALEC | ALECTOR INC | -- | $5,972.76 | 4,236 | BJ4LDC4 |
| 0.01% | TSVT | 2SEVENTY BIO INC | -- | $5,530.40 | 2,230 | BMTXV88 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $5,133.52 | 4,984 | BCZS820 |
| 0.01% | STRO | SUTRO BIOPHARMA INC | -- | $5,118.65 | 3,567 | BF12XC2 |
| 0.01% | NKTX | NKARTA INC | -- | $4,949.10 | 3,055 | BK80YJ8 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $4,830.35 | 1,865 | BSMLR16 |
| 0.01% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $4,574.51 | 15,634 | BWFZX59 |
| 0.01% | BMEA | BIOMEA FUSION INC | -- | $4,136.88 | 1,567 | BNKF6N0 |
| 0.01% | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $4,123.84 | 1,052 | BMF1LJ7 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,964.91 | 1,411 | BMTX3D7 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,922.47 | 2,126 | BNLYBJ7 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $3,919.05 | 2,903 | BMW5LX6 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,636.30 | 2,635 | BMDWW66 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $3,385.98 | 1,447 | BQ6C357 |
| 0.01% | INZY | INOZYME PHARMA INC | -- | $3,029.11 | 2,779 | BMVLGY1 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $2,849.37 | 2,567 | BLBR8D5 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $2,670.99 | 553 | BT7KGT6 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $2,564.16 | 5,342 | BF3NP05 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,308.22 | 5,031 | BJL38Z1 |
| -- | IGMS | IGM BIOSCIENCES INC | -- | $1,855.98 | 1,473 | BKS3SM8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $1,761.30 | 9,785 | BM9HFX3 |
| -- | QTTB | Q32 BIO INC | -- | $1,144.80 | 530 | BS2FKQ4 |
| 41.87% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 24,723,343 | -- | 5,585 | -- |
| 35.83% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,159,817 | -- | 4,780 | -- |
| 20.56% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 12,142,548 | -- | 2,743 | -- |
| 9.90% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 5,847,724 | -- | 1,321 | -- |
| 9.42% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 5,564,412 | -- | 1,257 | -- |
| 7.12% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 4,205,403 | -- | 950 | -- |
| -- | -- | TREASURY BILL | -- | $9,967,015.70 | 10,000,000 | BTBKBR5 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $4,771,322.37 | 4,771,322 | -- |
Index
as of 12/31/2024
- Total Number of Companies265
- Price/Earnings Ratio--
- Price/Book Ratio4.157
- Dividend Yield ( % )0.88
- Avg. Index Market Capitalization$5.58 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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