BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 1/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 9.81% | -6.82% | -15.88% | 9.81% | -1.10% | -3.16% | 0.64% | -2.11% | 14.62% | 04/07/2010 |
| BIB NAV | 9.75% | -7.11% | -15.96% | 9.75% | -1.12% | -3.31% | 0.62% | -2.13% | 14.61% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -14.25% | -19.94% | -13.65% | -9.84% | -9.84% | -14.06% | -3.57% | -1.96% | 13.98% | 04/07/2010 |
| BIB NAV | -14.45% | -20.03% | -13.70% | -10.00% | -10.00% | -14.09% | -3.57% | -1.97% | 13.97% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/20/2025- NAV $57.16
- NAV Change $+0.62
- Market Price $57.10
- Market Price Change $+0.65
- Trading Volume (M) 7,490
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/20/2025- NAV $57.16
- NAV Change $+0.62
- Market Price $57.10
- Market Price Change $+0.65
- Trading Volume (M) 7,490
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2024
Holdings
as of 2/20/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.94% | GILD | GILEAD SCIENCES INC | -- | $4,447,632.66 | 40,422 | 2369174 |
| 6.16% | AMGN | AMGEN INC | -- | $3,942,507.69 | 13,233 | 2023607 |
| 5.99% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,839,758.02 | 7,994 | 2931034 |
| 5.08% | REGN | REGENERON PHARMACEUTICALS | -- | $3,253,197.48 | 4,674 | 2730190 |
| 2.93% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,878,240.96 | 25,191 | 2989044 |
| 2.19% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,401,082.00 | 5,582 | B00FWN1 |
| 1.41% | ARGX | ARGENX SE - ADR | -- | $902,601.06 | 1,394 | BDVLM39 |
| 1.35% | BIIB | BIOGEN INC | -- | $863,604.00 | 6,300 | 2455965 |
| 1.15% | SMMT | SUMMIT THERAPEUTICS INC | -- | $735,498.70 | 31,895 | BMTVQS7 |
| 1.11% | UTHR | UNITED THERAPEUTICS CORP | -- | $709,372.16 | 1,931 | 2430412 |
| 1.10% | SNY | SANOFI-ADR | -- | $704,880.86 | 13,022 | 2964557 |
| 1.04% | ILMN | ILLUMINA INC | -- | $666,694.80 | 6,859 | 2613990 |
| 1.01% | INSM | INSMED INC | -- | $646,974.18 | 7,738 | 2614487 |
| 1.00% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $640,435.95 | 19,215 | BMVP7Y0 |
| 0.93% | INCY | INCYTE CORP | -- | $594,809.54 | 8,333 | 2471950 |
| 0.92% | ITCI | INTRA-CELLULAR THERAPIES INC | -- | $589,227.36 | 4,584 | BHCB0P4 |
| 0.89% | VTRS | VIATRIS INC | -- | $570,961.44 | 51,624 | BMWS3X9 |
| 0.88% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $566,541.39 | 8,243 | 2437071 |
| 0.88% | MRNA | MODERNA INC | -- | $561,537.04 | 16,648 | BGSXTS3 |
| 0.79% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $508,561.80 | 4,380 | 2623911 |
| 0.79% | TEM | TEMPUS AI INC | -- | $505,738.24 | 6,592 | BSLSJJ0 |
| 0.78% | BNTX | BIONTECH SE-ADR | -- | $500,754.24 | 4,248 | BK6H543 |
| 0.73% | ONC | BEIGENE LTD-ADR | -- | $467,887.20 | 1,916 | BYYWPW6 |
| 0.73% | MEDP | MEDPACE HOLDINGS INC | -- | $464,857.80 | 1,348 | BDCBC61 |
| 0.70% | SRPT | SAREPTA THERAPEUTICS INC | -- | $447,624.89 | 4,129 | B8DPDT7 |
| 0.69% | PCVX | VAXCYTE INC | -- | $444,678.24 | 5,392 | BKPVGH6 |
| 0.68% | EXEL | EXELIXIS INC | -- | $433,501.86 | 12,354 | 2576941 |
| 0.63% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $403,299.22 | 2,609 | BV9G6B8 |
| 0.56% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $357,476.40 | 2,616 | B4Q5ZN4 |
| 0.53% | ROIV | ROIVANT SCIENCES LTD | -- | $337,519.20 | 31,485 | BMW4NZ9 |
| 0.52% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $330,670.26 | 942 | BD59BS7 |
| 0.49% | HALO | HALOZYME THERAPEUTICS INC | -- | $316,379.52 | 5,508 | 2975098 |
| 0.48% | RVMD | REVOLUTION MEDICINES INC | -- | $307,399.24 | 7,274 | BL71K91 |
| 0.47% | BBIO | BRIDGEBIO PHARMA INC | -- | $300,917.68 | 8,176 | BK1KWG8 |
| 0.42% | AXSM | AXSOME THERAPEUTICS INC | -- | $270,464.50 | 2,095 | BYZR4X4 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $260,763.12 | 5,101 | BBBSBJ5 |
| 0.40% | BPMC | BLUEPRINT MEDICINES CORP | -- | $258,896.40 | 2,744 | BWY52P3 |
| 0.40% | GH | GUARDANT HEALTH INC | -- | $253,258.20 | 5,343 | BFXC911 |
| 0.39% | ALKS | ALKERMES PLC | -- | $248,393.50 | 6,997 | B3P6D26 |
| 0.36% | NUVL | NUVALENT INC-A | -- | $233,575.65 | 2,835 | BMVBZD3 |
| 0.36% | KRYS | KRYSTAL BIOTECH INC | -- | $227,544.52 | 1,246 | BD6JX35 |
| 0.35% | IONS | IONIS PHARMACEUTICALS INC | -- | $223,207.32 | 6,828 | BDJ0LS6 |
| 0.32% | VRNA | VERONA PHARMA PLC - ADR | -- | $205,408.00 | 3,200 | BYWPZK5 |
| 0.30% | SWTX | SPRINGWORKS THERAPEUTICS INC | -- | $192,974.60 | 3,220 | BGMGM89 |
| 0.29% | CRSP | CRISPR THERAPEUTICS AG | -- | $186,137.13 | 3,691 | BDHF4K6 |
| 0.28% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $177,697.60 | 3,995 | BJ62Z18 |
| 0.27% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $170,930.25 | 16,515 | BM9FJ13 |
| 0.26% | PTCT | PTC THERAPEUTICS INC | -- | $168,067.68 | 3,336 | B17VCN9 |
| 0.26% | RNA | AVIDITY BIOSCIENCES INC | -- | $167,984.92 | 5,164 | BMWHPY1 |
| 0.26% | ADMA | ADMA BIOLOGICS INC | -- | $164,401.92 | 10,224 | B9NSBM2 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $158,792.40 | 4,056 | BFZQ0L8 |
| 0.24% | ACLX | ARCELLX INC | -- | $153,330.57 | 2,337 | BPCJ1Q2 |
| 0.24% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $153,241.96 | 2,654 | BF2YWG4 |
| 0.24% | AKRO | AKERO THERAPEUTICS INC | -- | $152,650.44 | 3,018 | BK7Y2V9 |
| 0.24% | APLS | APELLIS PHARMACEUTICALS INC | -- | $152,523.00 | 5,380 | BYTQ6X1 |
| 0.23% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $147,882.32 | 4,012 | BDD19F8 |
| 0.23% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $145,966.26 | 7,194 | 2713317 |
| 0.22% | MRUS | MERUS NV | -- | $141,175.32 | 2,964 | BZBY005 |
| 0.21% | VCYT | VERACYTE INC | -- | $137,517.50 | 3,350 | BFTWZY0 |
| 0.21% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $137,504.36 | 3,533 | BMX9K07 |
| 0.21% | ALVO | ALVOTECH SA | -- | $135,053.10 | 11,543 | BPNTJ34 |
| 0.21% | DNLI | DENALI THERAPEUTICS INC | -- | $134,397.75 | 6,225 | BD2B4V0 |
| 0.20% | XENE | XENON PHARMACEUTICALS INC | -- | $129,954.00 | 3,300 | BRJ3GY4 |
| 0.20% | IMVT | IMMUNOVANT INC | -- | $129,857.50 | 6,350 | BJRFSB7 |
| 0.19% | BEAM | BEAM THERAPEUTICS INC | -- | $118,674.34 | 3,581 | BK6L288 |
| 0.18% | FOLD | AMICUS THERAPEUTICS INC | -- | $117,220.68 | 12,924 | B19FQ48 |
| 0.18% | VCEL | VERICEL CORP | -- | $115,951.85 | 2,135 | BSBMN89 |
| 0.18% | TWST | TWIST BIOSCIENCE CORP | -- | $115,675.28 | 2,566 | BGKG6G7 |
| 0.18% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $112,806.72 | 5,382 | BYQBFJ8 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $111,001.60 | 4,096 | BKY5JZ8 |
| 0.17% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $110,413.32 | 2,077 | BJDX8Y8 |
| 0.17% | IBRX | IMMUNITYBIO INC | -- | $109,720.52 | 30,143 | BNSP0B8 |
| 0.16% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $105,497.35 | 13,405 | BFNF1D6 |
| 0.16% | KYMR | KYMERA THERAPEUTICS INC | -- | $104,963.10 | 2,805 | BMPRZV5 |
| 0.16% | NVCR | NOVOCURE LTD | -- | $101,322.00 | 4,680 | BYSS4X4 |
| 0.16% | LGND | LIGAND PHARMACEUTICALS | -- | $99,804.18 | 818 | 2501578 |
| 0.15% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $99,073.26 | 2,574 | BDCBCD8 |
| 0.14% | TVTX | TRAVERE THERAPEUTICS INC | -- | $87,505.38 | 3,711 | BLFGJD5 |
| 0.13% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $86,178.30 | 2,470 | BKSGZN7 |
| 0.13% | JANX | JANUX THERAPEUTICS INC | -- | $84,375.90 | 2,270 | BMFX8Y7 |
| 0.13% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $84,115.62 | 8,958 | 2100362 |
| 0.13% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $83,362.50 | 2,470 | BCBVTX1 |
| 0.13% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $82,635.51 | 2,389 | B72ZBG4 |
| 0.13% | CGON | CG ONCOLOGY INC | -- | $82,487.06 | 2,923 | BRBCSP4 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $81,248.47 | 3,739 | BK0VHF6 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $80,953.74 | 2,734 | BL55460 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $80,582.88 | 1,654 | BMH5RL1 |
| 0.12% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $75,905.00 | 3,995 | BP8JSP4 |
| 0.12% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $75,727.73 | 5,681 | BRJZSK0 |
| 0.12% | WVE | WAVE LIFE SCIENCES LTD | -- | $74,755.34 | 6,598 | BYZG9R0 |
| 0.12% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $73,939.80 | 13,180 | BF0DMK7 |
| 0.11% | IRON | DISC MEDICINE INC | -- | $69,894.10 | 1,286 | BMGJZJ8 |
| 0.11% | ZLAB | ZAI LAB LTD-ADR | -- | $69,851.46 | 2,254 | BD9GVY0 |
| 0.11% | GRAL | GRAIL INC | -- | $69,347.52 | 1,452 | BSLSSX7 |
| 0.11% | GERN | GERON CORP | -- | $68,771.87 | 26,149 | 2370381 |
| 0.11% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $67,972.30 | 5,065 | BKX9VD3 |
| 0.11% | MNKD | MANNKIND CORP | -- | $67,359.66 | 11,901 | BF081J4 |
| 0.10% | APGE | APOGEE THERAPEUTICS INC | -- | $66,168.55 | 1,949 | BM9HHL5 |
| 0.10% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $65,135.30 | 2,081 | BNFWZS4 |
| 0.10% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $64,655.00 | 3,860 | BLB0YQ9 |
| 0.10% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $64,109.24 | 806 | BQ721R4 |
| 0.10% | DYN | DYNE THERAPEUTICS INC | -- | $61,569.99 | 4,401 | BN15WD1 |
| 0.09% | FTRE | FORTREA HOLDINGS INC | -- | $60,519.97 | 3,877 | BRXYZ57 |
| 0.09% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $60,182.47 | 2,573 | BQS9486 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $59,019.09 | 3,691 | BN7Q7R7 |
| 0.09% | ARDX | ARDELYX INC | -- | $58,584.24 | 10,242 | BN89V40 |
| 0.09% | VIR | VIR BIOTECHNOLOGY INC | -- | $58,359.00 | 5,955 | BK4PZ38 |
| 0.09% | SYRE | SPYRE THERAPEUTICS INC | -- | $56,921.40 | 2,540 | BQBBDY8 |
| 0.09% | ETNB | 89BIO INC | -- | $55,753.52 | 5,087 | BK1K484 |
| 0.09% | NVAX | NOVAVAX INC | -- | $54,948.96 | 6,938 | BJDQXG4 |
| 0.09% | ARVN | ARVINAS INC | -- | $54,669.12 | 2,976 | BDZ30Q0 |
| 0.08% | ANIP | ANI PHARMACEUTICALS INC | -- | $54,359.37 | 911 | BCDWBX6 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $53,961.25 | 4,405 | BYZM6C2 |
| 0.08% | TXG | 10X GENOMICS INC-CLASS A | -- | $53,499.68 | 4,628 | BKS3RS7 |
| 0.08% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $53,371.72 | 4,364 | BLB0YH0 |
| 0.08% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $53,162.06 | 6,382 | BJ5FZ74 |
| 0.08% | INDV | INDIVIOR PLC | -- | $53,023.02 | 5,898 | BP0BQQ5 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $52,227.60 | 3,065 | BMVLGP2 |
| 0.08% | PCRX | PACIRA BIOSCIENCES INC | -- | $51,428.52 | 1,998 | B3X26D8 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $51,137.44 | 1,712 | BLCD809 |
| 0.08% | SPRY | ARS PHARMACEUTICALS INC | -- | $49,511.34 | 4,203 | BMCR7V2 |
| 0.08% | OCUL | OCULAR THERAPEUTIX INC | -- | $49,314.50 | 6,802 | BNZB1X8 |
| 0.08% | INVA | INNOVIVA INC | -- | $48,969.70 | 2,710 | BDDXF67 |
| 0.08% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $48,491.19 | 6,193 | BFWLC09 |
| 0.07% | XNCR | XENCOR INC | -- | $47,796.33 | 3,027 | BGCYWN8 |
| 0.07% | REPL | REPLIMUNE GROUP INC | -- | $47,623.68 | 3,328 | BDDVW37 |
| 0.07% | HROW | HARROW INC | -- | $46,400.20 | 1,540 | BHNDW86 |
| 0.07% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $45,409.05 | 2,115 | BMFD115 |
| 0.07% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $42,882.15 | 3,945 | BDFKQ07 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $41,779.60 | 2,980 | BPCQZY9 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $41,471.50 | 1,394 | BX7RSN3 |
| 0.06% | GMAB | GENMAB A/S -SP ADR | -- | $40,683.72 | 1,813 | BBC9WC7 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $40,110.36 | 12,774 | BL53SR3 |
| 0.06% | EOLS | EVOLUS INC | -- | $39,971.08 | 2,734 | BDRJH21 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $39,907.23 | 1,457 | BMGTLY5 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $39,713.22 | 5,274 | B8K7T65 |
| 0.06% | COGT | COGENT BIOSCIENCES INC | -- | $38,637.84 | 4,776 | BLR6XK8 |
| 0.06% | PRTA | PROTHENA CORP PLC | -- | $35,441.00 | 2,324 | B91XRN2 |
| 0.06% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $35,402.62 | 1,798 | BRXB0C0 |
| 0.06% | AVDL | AVADEL PHARMACEUTICALS | -- | $35,294.49 | 4,167 | BDGMC59 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $31,829.56 | 3,667 | BYTYP72 |
| 0.05% | CVAC | CUREVAC NV | -- | $31,825.84 | 9,703 | BN4RD42 |
| 0.05% | CSTL | CASTLE BIOSCIENCES INC | -- | $31,693.80 | 1,212 | BKLCWZ3 |
| 0.05% | RLAY | RELAY THERAPEUTICS INC | -- | $29,615.69 | 7,241 | BN2R582 |
| 0.05% | LENZ | LENZ THERAPEUTICS INC | -- | $29,603.78 | 1,187 | BQV0J03 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $29,556.54 | 9,659 | BMFJJ97 |
| 0.04% | VERV | VERVE THERAPEUTICS INC | -- | $28,665.63 | 3,661 | BNKGXX2 |
| 0.04% | CRMD | CORMEDIX INC | -- | $28,424.14 | 2,627 | BJ0LT31 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $28,211.44 | 8,201 | BZ0QMB7 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $27,975.42 | 2,189 | BMVNDH9 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $27,408.45 | 3,363 | BYZD465 |
| 0.04% | QURE | UNIQURE NV | -- | $27,332.64 | 2,109 | BJFSR88 |
| 0.04% | MNMD | MIND MEDICINE MINDMED INC | -- | $25,922.42 | 3,169 | BPQYY97 |
| 0.04% | ABSI | ABSCI CORP | -- | $25,783.92 | 4,968 | BN94K69 |
| 0.04% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $25,598.56 | 6,448 | BLR7H87 |
| 0.04% | PGEN | PRECIGEN INC | -- | $24,953.99 | 12,667 | BKM5C84 |
| 0.04% | ANAB | ANAPTYSBIO INC | -- | $24,832.92 | 1,316 | BDRW1L7 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $24,229.30 | 6,134 | BMCWKZ2 |
| 0.04% | OMER | OMEROS CORP | -- | $24,063.44 | 2,504 | B4NB858 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $23,829.09 | 1,383 | BQS7491 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $23,099.06 | 3,382 | BFYQFJ2 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $23,039.70 | 2,518 | BM90J52 |
| 0.04% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $22,836.00 | 1,903 | BKDQKM6 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $22,820.85 | 3,055 | BKVDFF7 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $22,429.12 | 2,108 | BD06CS0 |
| 0.03% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $21,571.00 | 1,100 | BQB9HM8 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $21,121.12 | 1,616 | BP81RK8 |
| 0.03% | HUMA | HUMACYTE INC | -- | $20,876.25 | 5,567 | BMYTJP4 |
| 0.03% | HCM | HUTCHMED CHINA-ADR | -- | $20,618.85 | 1,345 | BYXV9H7 |
| 0.03% | RAPP | RAPPORT THERAPEUTICS INC | -- | $20,592.00 | 1,584 | BR3T9B6 |
| 0.03% | MLYS | MINERALYS THERAPEUTICS INC | -- | $20,584.80 | 2,160 | BP9N0G0 |
| 0.03% | TBPH | THERAVANCE BIOPHARMA INC | -- | $20,537.16 | 2,126 | BMNDK09 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $20,446.09 | 9,067 | BFZNYB7 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $20,393.88 | 3,076 | BFY7DC4 |
| 0.03% | OABI | OMNIAB INC | -- | $20,319.56 | 5,237 | BN13S71 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $20,236.57 | 881 | BL95N25 |
| 0.03% | STOK | STOKE THERAPEUTICS INC | -- | $20,049.56 | 2,294 | BJQ05Z6 |
| 0.03% | SVRA | SAVARA INC | -- | $19,965.18 | 7,422 | BYXGN81 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $19,813.32 | 1,171 | BKC9SX3 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $19,672.73 | 638 | BPBPCG8 |
| 0.03% | URGN | UROGEN PHARMA LTD | -- | $19,556.46 | 1,826 | BZ7PJQ1 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,422.52 | 11,843 | B4N8MH9 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $19,346.62 | 1,754 | BM7V485 |
| 0.03% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $18,973.80 | 2,988 | BMGS7L1 |
| 0.03% | SAGE | SAGE THERAPEUTICS INC | -- | $18,954.65 | 2,651 | BP4GNK9 |
| 0.03% | SIGA | SIGA TECHNOLOGIES INC | -- | $18,880.20 | 3,085 | 2107437 |
| 0.03% | TKNO | ALPHA TEKNOVA INC | -- | $18,424.94 | 2,306 | BP7L561 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $18,087.30 | 2,310 | BLFBZ32 |
| 0.03% | MXCT | MAXCYTE INC | -- | $18,061.56 | 4,561 | BKMQF66 |
| 0.03% | ERAS | ERASCA INC | -- | $17,854.34 | 12,229 | BNLYBF3 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $17,759.62 | 5,674 | BPBJFM7 |
| 0.03% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $17,589.39 | 2,653 | BP7KZP7 |
| 0.03% | ORKA | ORUKA THERAPEUTICS INC | -- | $17,077.92 | 1,514 | BKVF0J2 |
| 0.03% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $16,836.30 | 8,634 | BFMLGR4 |
| 0.03% | ATXS | ASTRIA THERAPEUTICS INC | -- | $16,647.62 | 2,441 | BMYRFN8 |
| 0.03% | PSNL | PERSONALIS INC | -- | $16,610.37 | 3,059 | BJQ0608 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $16,488.43 | 2,161 | BP81R42 |
| 0.03% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $16,392.86 | 2,959 | BJLKVS6 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $16,198.38 | 606 | B292NQ7 |
| 0.02% | TRVI | TREVI THERAPEUTICS INC | -- | $15,950.40 | 3,323 | BJH9ZN0 |
| 0.02% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $15,893.29 | 763 | BQD3J33 |
| 0.02% | RGNX | REGENXBIO INC | -- | $15,779.84 | 2,144 | BZ0G875 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $15,773.10 | 8,526 | BBNBTD2 |
| 0.02% | TERN | TERNS PHARMACEUTICALS INC | -- | $15,173.62 | 3,674 | BMDJ0C9 |
| 0.02% | CDXS | CODEXIS INC | -- | $14,986.68 | 3,518 | B5LL2C2 |
| 0.02% | TSHA | TAYSHA GENE THERAPIES INC | -- | $14,538.60 | 8,865 | BNC1BX1 |
| 0.02% | TRML | TOURMALINE BIO INC | -- | $13,693.59 | 1,107 | BQ80NC6 |
| 0.02% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $13,149.90 | 6,921 | B3MZ6K5 |
| 0.02% | ANNX | ANNEXON INC | -- | $13,051.96 | 4,612 | BMVV9R5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,933.52 | 2,404 | BMF7DT9 |
| 0.02% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $12,593.32 | 2,479 | BMZ4LN0 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $12,274.50 | 2,450 | BMFK3H6 |
| 0.02% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $12,259.80 | 2,780 | BYP80F1 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $12,074.76 | 3,946 | BYVQJ96 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $11,944.35 | 6,985 | BN4JN37 |
| 0.02% | ITOS | ITEOS THERAPEUTICS INC | -- | $11,833.36 | 1,582 | BMWXFT4 |
| 0.02% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $11,736.60 | 7,572 | BPG5P75 |
| 0.02% | YMAB | Y-MABS THERAPEUTICS INC | -- | $11,705.52 | 1,938 | BG31GH0 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $11,473.56 | 3,654 | BLN9Z50 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $11,384.80 | 4,280 | BZC0D70 |
| 0.02% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $11,350.28 | 15,634 | BWFZX59 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $11,323.78 | 2,522 | B12W3P6 |
| 0.02% | TNGX | TANGO THERAPEUTICS INC | -- | $11,287.35 | 4,645 | BP2P6L0 |
| 0.02% | NGNE | NEUROGENE INC | -- | $11,130.33 | 643 | BS2F741 |
| 0.02% | ALMS | ALUMIS INC | -- | $10,475.46 | 2,042 | BPLQG36 |
| 0.02% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $10,447.36 | 2,968 | BPCK358 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $10,362.00 | 1,727 | BQHN6C7 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $10,282.14 | 17,310 | 2301938 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $10,170.00 | 2,034 | BL5B6Z1 |
| 0.02% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,070.64 | 2,364 | BY7RB53 |
| 0.02% | CMPS | COMPASS PATHWAYS PLC | -- | $9,992.54 | 2,201 | BMC3HS7 |
| 0.01% | SLRN | ACELYRIN INC | -- | $9,415.63 | 4,339 | BQPF874 |
| 0.01% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $9,335.33 | 1,999 | BKLXFX5 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $9,137.44 | 3,056 | BKX9NQ0 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $9,018.66 | 2,758 | BMXNGZ6 |
| 0.01% | INBX | INHIBRX BIOSCIENCES INC | -- | $8,025.60 | 627 | BNSP8K3 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $7,970.16 | 12,076 | BN6MB18 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $7,931.35 | 2,635 | BMDWW66 |
| 0.01% | ALEC | ALECTOR INC | -- | $7,878.96 | 4,236 | BJ4LDC4 |
| 0.01% | ACRV | ACRIVON THERAPEUTICS INC | -- | $7,856.55 | 1,343 | BP2TPK4 |
| 0.01% | MGNX | MACROGENICS INC | -- | $7,827.84 | 2,718 | BFDV8K0 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $7,700.28 | 4,984 | BCZS820 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $7,676.08 | 916 | B9L5200 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $7,356.26 | 3,571 | BZ8FPH3 |
| 0.01% | CRGX | CARGO THERAPEUTICS INC | -- | $7,346.79 | 1,991 | BQHN2F2 |
| 0.01% | SCPH | SCPHARMACEUTICALS INC | -- | $7,260.96 | 2,161 | BYX2Z16 |
| 0.01% | THRD | THIRD HARMONIC BIO INC | -- | $6,984.58 | 1,951 | BNNPQY8 |
| 0.01% | NKTX | NKARTA INC | -- | $6,568.25 | 3,055 | BK80YJ8 |
| 0.01% | STRO | SUTRO BIOPHARMA INC | -- | $6,527.61 | 3,567 | BF12XC2 |
| 0.01% | TSVT | 2SEVENTY BIO INC | -- | $5,976.40 | 2,230 | BMTXV88 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $5,831.41 | 1,447 | BQ6C357 |
| 0.01% | BMEA | BIOMEA FUSION INC | -- | $5,719.55 | 1,567 | BNKF6N0 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $5,296.60 | 1,865 | BSMLR16 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $4,655.94 | 2,126 | BNLYBJ7 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $4,180.32 | 2,903 | BMW5LX6 |
| 0.01% | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $3,987.08 | 1,052 | BMF1LJ7 |
| 0.01% | INZY | INOZYME PHARMA INC | -- | $3,529.33 | 2,779 | BMVLGY1 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,491.12 | 2,567 | BLBR8D5 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $3,019.38 | 553 | BT7KGT6 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,843.52 | 5,031 | BJL38Z1 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $2,820.58 | 5,342 | BF3NP05 |
| -- | IGMS | IGM BIOSCIENCES INC | -- | $2,047.47 | 1,473 | BKS3SM8 |
| -- | PEPG | PEPGEN INC | -- | $2,031.84 | 1,411 | BMTX3D7 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $1,761.30 | 9,785 | BM9HFX3 |
| -- | QTTB | Q32 BIO INC | -- | $1,287.90 | 530 | BS2FKQ4 |
| 38.96% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 24,952,381 | -- | 5,417 | -- |
| 36.14% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 23,151,314 | -- | 5,026 | -- |
| 19.73% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 12,635,108 | -- | 2,743 | -- |
| 11.48% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 7,351,671 | -- | 1,596 | -- |
| 9.50% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 6,084,936 | -- | 1,321 | -- |
| 6.83% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 4,375,995 | -- | 950 | -- |
| 4.91% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP MORGAN STANLEY & CO. INTERNATIONAL PLC | 3,146,110 | -- | 683 | -- |
| -- | -- | TREASURY BILL | -- | $9,953,904.20 | 10,000,000 | BTBKBR5 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $7,986,618.95 | 7,986,619 | -- |
Index
as of 12/31/2024
- Total Number of Companies265
- Price/Earnings Ratio--
- Price/Book Ratio4.157
- Dividend Yield ( % )0.88
- Avg. Index Market Capitalization$5.58 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
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